Middlesbrough travel to Old Trafford to as they look to cause an upset and progress to the next round of the Capital One Cup.

Boro host Charlton
Boro are to take 10,000 fans to Old Trafford

Here are THREE things to look out for in the game:

1) A number of changes from Aitor Karanka

The Spaniard is know for rotating his side but he confirmed after his side's 3-1 win over Wolves that he would be making several changes because of injuries and to avoid suspensions.

Albert Adomah, Stewart Downing, Adam Forshaw and Cristhian Stuani are all carrying injuries and could be rested by Karanka at Old Trafford.

As well as injuries, the Boro boss has to take into account the four players who are just one booking away from suspension. Daniel Ayala, Adam Clayton, Grant Leadbitter and Diego Fabbrini are all on four cautions and Karanka may also leave them out, depending on his options.

2) Manchester United to name a strong side

Louis Van Gaal showed in the last round against Ipswich that he is taking the competition seriously and that he won't play youth players just because they are facing a side a division below them.

Wayne Rooney, Juan Mata, Andre Herrera and David de Gea all featured in that game along with a number of other first team stars.

While the Dutchman is expected to make changes from side that drew 0-0 with Manchester City on Sunday, he is still expected to name a strong starting XI as he seeks his first silverware since becoming the Red Devils manager.

3) Boro setting out to win the game

A lot of teams travel to Old Trafford to park the bus and leave with a draw. However, Middlesbrough boss Aitor Karanka will have a plan to win the game.

They shocked Manchester City last season won 2-0 with a mix of defensive solidity and some fine counter attacking football and you can expect something pretty similar on Wednesday night.

Whether they can repeat that result is another matter but Karanka will ensure that his players believe that they can do it, and being cheered on by 10,000 Teessiders could help their cause.

Manchester United and Middlesbrough fans......What are your predictions for the match? Will United meet expectations with a victory? Can Boro shock Van Gaal's men? Let us know what you think in the comments below!